Professor of Pharmacology & Toxicology
Vacek Chair in Pharmacology
Work in the Gore Laboratory focuses on effects of endocrine-disrupting chemicals (EDCs) on the neuroendocrine control of reproduction and behavior.
Current research in a rat model seeks to understand how prenatal exposure to environmental endocrine disruptors (EDCs) changes the developing brain by inducing molecular and cellular changes to neurons in the hypothalamus and other brain regions. Beyond this work on direct effects of EDCs on developing individuals, we seek to understand how EDC exposures can lead to multigenerational behavioral changes through epigenetic actions on the germline and gametes, the precursors to ova and sperm, which become the next generation.
Our team uses a variety of techniques, including behavioral, physiological, neuroanatomical, immunohistochemical, and molecular approaches such as gene expression, transcriptomics, epigenetic profiling, DNA methylation, RNAscope and hormone assays.
See also: On Campus Feature Q&A with Dr. Gore
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Admin: 512-471-5096
Lab: 512-471-6311
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The University of Texas at Austin
BME 3.510B
107 W. Dean Keeton, C0875
Austin, TX 78712
FEDEX Address:
107 W. Dean Keeton St.
BME 3.510B
The University of Texas at Austin
Austin, TX 78712