Professor of Pharmacology & Toxicology
Vacek Chair in Pharmacology
Revco Foundation Fellow in Pharmacy
Work in the Gore Laboratory focuses on effects of endocrine-disrupting chemicals (EDCs) on the neuroendocrine control of reproduction and behavior.
Current research in a rat model seeks to understand how prenatal exposure to environmental endocrine disruptors (EDCs) changes the developing brain by inducing molecular and cellular changes to neurons in the hypothalamus and other brain regions. Beyond this work on direct effects of EDCs on developing individuals, we seek to understand how EDC exposures can lead to multigenerational behavioral changes through epigenetic actions on the germline and gametes, the precursors to ova and sperm, which become the next generation.
Our team uses a variety of techniques, including behavioral, physiological, neuroanatomical, immunohistochemical, and molecular approaches such as gene expression, transcriptomics, epigenetic profiling, DNA methylation, RNAscope and hormone assays.
See also: On Campus Feature Q&A with Dr. Gore
2017 Texas Student Research Showdown
Min Ji and Lexi study the ways that endocrine-disrupting chemicals effect individuals and their offspring. Watch their video
"Endocrine-disrupting chemicals”
Watch Erin's video
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The University of Texas at Austin
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