Collaborative Areas of Research Excellence (CARE)

Both basic science and clinical research is underway on a broad-range of topics including drug addiction, cancer, toxicology, infectious disease, pharmacy policy, mental health, and pharmaceutical development.

Collaborations within the college and within the University of Texas help to enrich research opportunities.

Collaborative Areas of Research Excellence (CARE)

Chemical Biology & Drug Discovery

This collaborative research area is focused on the discovery and optimization of novel chemical leads targeted to disease-related proteins for research tools and therapeutics, and the training of the next generation of drug discovery scientists.

Environmental & Developmental Mechanisms of Health and Disease

Environmental toxicants, pollutants, and chemicals can profoundly affect health and disease. Together with an individual’s genome and other influences (social, behavioral, hormonal), exposures to exogenous environmental factors predispose for cancer, endocrine disorders, and neurobehavioral and physiological disturbances.

Developmental exposure is particularly problematic due to the propensity of toxicants to cause epigenetic, genetic, and molecular reprogramming changes that set the stage for subsequent disease. Faculty in this collaborative research area have a common goal of determining effects of environmental exposures on physiology, pathophysiology, and behavior, and deciphering the underlying cellular, biochemical, and molecular responses.

Health Outcomes, Economic and Equity Research

The overall goal of the research of this collaborative group of faculty is to improve the public’s health and outcomes through the efficient use of scarce health care resources, and to reduce health disparities through practice-, population-, and policy-based research.

Infectious Diseases

This group of Pharmacy faculty has focused research efforts in the area of infectious disease to understand pathogenic mechanisms, to discover and develop protein and small molecule therapeutics, and to develop other anti-infective technologies including novel vaccination methods.

Molecular Mechanisms of Cancer

The goal of research in this focus area is to conduct basic research on mechanisms of how cancer develops and progresses and to identify new molecular targets for cancer prevention and treatment. In addition, researchers are also involved in developing novel agents and drug delivery systems for cancer prevention and treatment. Finally, there is an emphasis on training the next generation of cancer researchers.

Neuropharmacology & Addiction

The goal of research in this focus area is to conduct basic research on mechanisms of how drugs of abuse, particularly alcohol, produce their rewarding and behavioral effects through changes in brain function at multiple levels of analysis: molecular, cellular, circuit, systems, neurochemical, and behavioral.

By producing fundamental new knowledge on these mechanisms, new and improved therapies could be developed for addiction and other brain diseases. In addition, the faculty in this area are committed to recruiting, training, and retaining the next generation of diverse researchers in neuropharmacology and addiction.

Translational Research in Drug Delivery

This collaborative research area is focused on bridging basic science and clinical therapeutics leading to the discovery of new drug delivery systems that can be brought to market.