Academic Year 2019 (9/2018-9/2020)
- N. Kittikunakorn, T.Z. Liu, F. Zhang, “Twin-screw melt granulation: current progress and challenges”, International Journal of Pharmaceutics, 588: 119670 (2020)
- T.Z. Liu, S. Paul, B.T. Beeson, J. Alexander, F.Y. Yang, V. Bi, T. Durig, C. Sun, F. Zhang, “Effect of hydroxypropyl cellulose level on twin-screw melt granulation of acetaminophen”, AAPS PharmSciTech, 21:240 (2020)
- M.Y. Li, F. Meng, Y. Tsutsumi, J.P. Amoureux, W. Xu, X.Y. Lu, F. Zhang, Y.C Su, “Understanding molecular interactions in rafoxanide-povidone amorphous solid dispersions from ultrafast magic angle spinning NMR”, Molecular Pharmaceutics, 17: 2196-2207 (2020)
- M.B. Lowinger, E.Y. Maier, R.O. Williams III, F. Zhang, “Hydrophilic polyurethanes are an effective tool for gastric retention independent of drug release rate”, Journal of Pharmaceutical Sciences, 109:1967-1977 (2020)
- X. Liu, X.Y Lu, Y.C. Su, E. Kun, F. Zhang, “Clay-polymer nanocomposites prepared by reactive melt extrusion for sustained drug release”, Pharmaceutics, 12:51 (2020)
- S.K. Rahimi, S. Paul, C. Sun, F. Zhang, “The role of the screw profile on granular structure and mixing efficiency of a high-dose hydrophobic drug formulation during twin screw wet granulation”, International Journal of Pharmaceutics, 575:118958 (2020)
Academic Year 2018 (9/2018-8/2019)
- R. Lagle, P. Tipsay, V.K. Shanker, A. Maurya, M. Pimparade, S. Bandari, F. Zhang, S. N. Murthy, “Preparation and evaluation of cefuroxime axitel gastro-retentive floating drug delivery system for improved delivery via hot melt extrusion technology”, International Journal of Pharmaceutical Science, Submitted for review (March 2019)
- N. Kittikunakorn, C. Sun, and F. Zhang*, “Process-Induced Transformation and Chemical Degradation of Gabapentin during Continuous Twin-Screw Melt Granulation”, European Journal of Pharmaceutical Science, 131:243-253 (2019).
- N. Kittikunakorn, J.J. Koleng III, T. Listro, C. Sun, and F. Zhang*, “Effects of Thermal Binders on Chemical Stability and Tabletability of Gabapentin Granules Prepared by Twin Screw Melt Granulation”, International Journal of Pharmaceutics, 559:37-47 (2019).
- M. Lowinger, Y.C. Su, X.Y. Lu, R. Williams, and F. Zhang*, “Can Drug Release Rate from Implants be Tailored Using Polyurethane Mixture?”, International Journal of Pharmaceutics, 557:390-411 (2019).
- F. Meng, R. Ferreira, F. Zhang*, “Effect of Surfactant Level on Properties of Celecoxib Amorphous Solid Dispersions”, Journal of Drug Delivery Science and Technology, 49:301-307 (2019).
- F. Meng, Z.F. Jing, R. Ferreira, P.Y. Ren, and F. Zhang*, “Investigating the Association Mechanism between Rafoxanide and Povidone”, Langmuir, (34) 13971-13978 (2018).
- A. Haser, B. Haight, A. Berghaus, A. Machado, C. Martin, and F. Zhang*, “Scale-up and In-line Monitoring during Continuous Melt Extrusion of an Amorphous Solid Dispersion”, AAPS PharmSciTech, 19:7 2818-2827 (2018) .
- X. Liu, X.Y. Ma, E. Kun, X.D. Guo, Z.X. Yu, and F. Zhang*, “Influence of Lidocaine Forms (Salt vs. Freebase) on Properties of Drug–Eudragit L100-55 Extrudates Prepared by Reactive Melt Extrusion”, International Journal of Pharmaceutics, (547) 291-302 (2018).
- M. Bookwala, P. Thipsay, S. Ross, F. Zhang, S. Bandari, and M. Repka, “Preparation of a Crystalline Salt of Indomethacin and Tromethamine by Hot Melt Extrusion Technology”, European Journal of Pharmaceutics and Biopharmaceutics, 131:109-119 (2018)
Academic Year 2017 (9/2017-8/2018)
- N.R. Dumpa, S. Sarabu, S. Bandari, F. Zhang, and M. Repka, “Chronotherapeutic Drug Delivery of Ketoprofen and Ibuprofen for Improved Treatment of Early Morning Stiffness in Arthritis Using Hot-Melt Extrusion Technology”, AAPS PharmSciTech, Epub ahead of print (2018)
- M.B. Lowinger, S.E. Barrett, F. Zhang* and R.O. Williams, “Sustained Release Drug Delivery Applications of Polyurethanes”, Pharmaceutics, 9:10 (2) (2018)
- X. Liu, M. Li, H. Smyth, and F. Zhang*, “Otic Drug Delivery Systems: Formulation Principles and Recent Development”, Drug Development and Industrial Pharmacy, 25:1-4 (2018)
- N. Kittikunakorn, J. DiNunzio, C. Martin, and F. Zhang*, “Process, Challenges and the Futures of Twin-Screw Granulation for Manufacturing Oral Tablets and Capsules”, Cover Story – Formulation Design and Development Section, AAPS Newsmagazine, 12-18, March 2018
- A. Haser and F. Zhang*, “New Strategies for Improving the Development and Performance of Amorphous Solid Dispersions”, AAPS PharmSciTech 19(3):9178-990 (2018)
- A. Haser, T. Cao, J. Lubach, and F. Zhang*, “In situ Salt Formation for Improved Chemical Stability and Dissolution Performance of a Meloxicam-Copovidone Amorphous Solid Dispersion”, Molecular Pharmaceutics, 15:1226-37 (2018)
- N. Mendonsa, S. Bandari, S. Murthy, F. Zhang and M. Repka, “Development of Poloxamer Gel Formulation via Hot-Melt Extrusion Technology”, International Journal of Pharmaceutics, 537:122-131 (2017)
- X. Feng and F. Zhang*, “Twin-screw Extrusion of Sustained-release Dosage Forms and Medical Implants”, Drug Delivery and Translational Science, 8(6):1694-1716 (2018)
- X. Liu, F. Xing, R.O. Williams, and F. Zhang* “Characterization of Amorphous Solid Dispersions”, Journal of Pharmaceutical Investigation, 48:19-41 (2018)
- B. Lang, X. Feng, and F. Zhang*, “Extended-release Dosage Forms Prepared Using Twin-screw Extrusion”, Chapter 10, Pharmaceutical Extrusion Technology, 2nd Edition, Edited by I. Ghebre-Sellassie, C. Martin, F. Zhang and J. DiNunzio, CRC Press, Taylor & Francis Group (2018)
Academic Year 2016 (9/2016-8/2017)
- F. Meng, J. Meckel and F. Zhang*, “Investigation of Itraconazole Ternary Amorphous Solid Dispersions Based on Povidone and Carbopol”, European Journal of Pharmaceutical Science, 106: 413-421 (2017)
- F. Meng. T.Z. Liu, E. Schneider, S. Alzobaidi, M. Gil and F. Zhang*, “Self-association of Rafoxanide in Aqueous Media and a Novel Method for Preparing Amorphous Solid Dispersions”, Molecular Pharmaceutics, 14: 1790-1799 (2017)
- A. Haser, T. Cao, J. Lubach, T. Listro, L. Acquarelo, F. Zhang*, “Melt Extrusion vs. Spray Drying: The Effect of Processing Methods on Crystalline Content of Naproxen-Povidone formulations”. European Journal of Pharmaceutical Science. 102: 115-125 (2017)
- A. Haser, S.Y. Huang, T. Listro, D. White and F. Zhang*, “An Approach for Chemical Stability during Melt Extrusion of a Drug Substance with a High Melting Point”, International Journal of Pharmaceutics. 524: 55-64 (2017)
- X. Liu, L. Zhou and F. Zhang*, “In-situ Salt Formation during Reactive Melt Extrusion Improve the Dissolution Performance and Physical Stability of Naproxen Amorphous Solid Dispersions”, Molecular Pharmaceutics 14: 658-675 (2017)
- M.J. McGinity, J. Floyd, J. W. McGinity and F. Zhang, “Implant Composition for the Unidirectional Delivery of Drugs to Brain”, Drug Development and Industrial Pharmacy, 43 (9):1421-1429 (2017)
- B. Chen, L. Zhu, F. Zhang and Y. Qiu, “Process Development and Scale-up: Twin Screw Extrusion”, Chapter 31, Developing Solid Oral Dosage Forms: Pharmaceutical Theory & Practice, 2nd Edition, Ed. Y. Qiu, Y. Chen, G. Zhang, L. Yu and R. Mantri, pp 821-868, 48 total pages, Elsevier (2016)
- A. Haser, J. C. DiNunzio, C. Martin, J.W. McGinity, and F. Zhang*, “Melt Extrusion”, Chapter 9, Formulating Poorly Water Soluble Drugs, 2nd Edition, AAPS Advances in Pharmaceutical Sciences, Series 3, Ed. R. O. Williams, A. B. Watts and D. A. Miller, pp. 383-435, 52 total pages, AAPS Press, Springer, (2016)
Academic Year 2015 (9/2015-8/2016)
- F. Zhang*, F. Meng, Z.Y. Wang and W. NA, “Interpolymer Complexation between Copovidone and Carbopol and Its Effect on Drug Release from Matrix Tablets”, Drug Development and Industrial Pharmacy, 43(2): 190-203 (2016)
- J. Maincent and F. Zhang*, “Recent Advances in Abuse-Deterrent Technologies for the Delivery of Opioids”, International Journal of Pharmaceutics, 510(1): 57-72 (2016)
- F. Zhang*, J. Lubach, W. NA, S. Momin, “Interpolymer complexation between PolyOx and Carbopol, and Its Effect on Drug Release from Matrix Tablets”, Journal of Pharmaceutical Sciences, 105(8): 2386-96 (2016)
- F. Zhang*, F. Meng, J. Lubach, J. Koleng, W. NA, “Properties and mechanisms of drug release from matrix tablets containing poly(ethylene oxide) and poly(acrylic acid) as release retardants”, European Journal of Pharmaceutics and Biopharmaceutics, 105: 97-105 (2016)
- F. Zhang* and M. Repka “Pharmaceutical Thermal Processing”, AAPS PharmSciTech, 17(1): 1-2 (2016), Invited publication
- H. Surasarang, J. Keen, S.Y. Huang, F. Zhang, J.W. McGinity and R.O. Williams, “Hot Melt Extrusion versus Spray Drying: Hot Melt Extrusion Degrades Albenazole”. Drug Development and Industrial Pharmacy, 43(5): 797-811 (2016)
- A. Vo, X. Feng, J. Morott, M. Pimparade, R. Tiwari, F. Zhang and M. Repka “A novel floating controlled release drug delivery system prepared by hot-melt extrusion”, European Journal of Pharmaceutics and Biopharmaceutics, 98: 108-121, (2016)
- A. Alshetaili, B.K. Almutairy, R.V. Tiwari, J.T. Morott, S.M. Alshehri, X. Feng, B.B. Alsulays, J.B. Park, F. Zhang and M. Repka, “Preparation and evaluation of hot-melt extruded patient-centric ketoprofen mini-tablets”, Current Drug Delivery, 13(5): 730-741, (2016)
Academic Year 2014 (9/2014-8/2015)
- F. Zhang* “Physicochemical properties and mechanisms of drug release from melt-extruded granules consisting of chlorpheniramine maleate and Eudragit® FS, Drug Development and Industrial Pharmacy, 42(4), 563-571 (2016)
- F. Zhang* “Melt-extruded Eudragit® FS-based granules for colonic drug delivery”, AAPS PharmSciTech, 17(1), 56-67 (2016), Invited publication
Prior to joining UT Austin
- D. Gena, E Nauka, F. Zhang, S. Kothari, M. Xie, “Assessment of Granulation Technologies for an API with Poor Physical Properties”, Drug Development and Industrial Pharmacy, June 2 (2012)
- J.C. DiNunzio, C. Martin, F. Zhang, “Melt Extrusion: Shaping Drug Delivery in the 21st Century”, Pharmaceutical Technology, November Supplement, S30-37 (2010)
- M.A. Repka, S. Thumma, S.B. Upadye, S. Kumar, M.M. Crowley, F. Zhang, C. Martin, J.W. McGinity, “Pharmaceutical Applications of Hot-Melt Extrusion: Part II”, Drug Development and Industrial Pharmacy, 33 (10): 1043-1057 (2007)
- M.M. Crowley, F. Zhang, M.A. Repka, S. Thumma, S.B. Upadye, S. Kumar, J.M. McGinity, and C. Martin, “Pharmaceutical Applications of Hot-Melt Extrusion: Part I”, Drug Development and Industrial Pharmacy, 33 (9): 909-926 (2007)
- V. Mahagunna, J.M McDermott, F. Zhang and F. Ochoa, “Investigation of Product Quality between Extemporaneously Compounded Progesterone Vaginal Suppositories and an Approved Progesterone Vaginal Gel”, Drug Development and Industrial Pharmacy, 30 (10): 1069-1078 (2004)
- M.M. Crowley, F. Zhang, J.J. Koleng and J.W. McGinity, “Stability of Polyethylene Oxide in Matrix Tablets Prepared by Hot-Melt Extrusion”, Biomaterials, 23 (21): 4241-4248 (2002)
- J.P. Liu, F. Zhang, and J.W. McGinity, “Properties of Lipophilic Matrix Tablets Containing Phenylpropanolamine Hydrochloride Prepared by Hot-Melt Extrusion”, European Journal of Pharmaceutics and Biopharmaceutics, 52 (2): 181-190 (2001)
- J.W. McGinity, F. Zhang, M.A. Repka and J.J. Koleng, “Hot-Melt Extrusion as a Pharmaceutical Process”, American Pharmaceutical Review, Summer Issue (2001)
- F. Zhang and J.W. McGinity, “Properties of Hot-Melt Extruded Theophylline Tablets Containing Poly(vinyl acetate)”, Drug Development and Industrial Pharmacy, 26 (9): 931-942 (2000)
- J.W. McGinity, F. Zhang, M.A. Repka, and J.J. Koleng, “Thermal Processing of Pharmaceutical Powders”, Pharmaceutical Technology Japan, 16 (6): 69-85 (2000)
- F. Zhang and J.W. McGinity, “Properties of Sustained Release Tablets Prepared by Hot-Melt Extrusion”, Pharmaceutical Development and Technology, 4 (2): 241‑249 (1999)
- A.N. Carolyn, F. Zhang, and J.W. McGinity, “Hot Melt Extrusion of Acrylic Films”, Pharmaceutical Research, 13 (5): 804-808 (1996)
- M.A. Repka, J.J. Koleng, F. Zhang, J.W. McGinity “Hot Melt Extrusion Technology”, Encyclopedia of Pharmaceutical Science and Technology, 4thEdition, Ed. J. Swarbrick, pp. 1855-1876, 22 total pages, CRC Press (2013)
- F. Zhang and J.C. DiNunzio, “Solubilized Formulation”, Chapter 5, Formulating Poorly Water Soluble Drugs, 1st Edition, AAPS Advances in Pharmaceutical Sciences Series, Series 3, , 1st Ed. R. O. Williams, A. B. Watts and D. A. Miller, pp. 171-208, 38 total pages, AAPS Press, Springer (2012)
- F. Zhang and J.C. DiNunzio, F. Zhang, C. Martin, J.W. McGinity. “Melt Extrusion”, Chapter 9, Formulating Poorly Water Soluble Drugs, 1st Edition, AAPS Advances in Pharmaceutical Sciences Series, Series 3, Ed. R. O. Williams, A. B. Watts and D. A. Miller, pp. 311-362, 52 total pages, AAPS Press, Springer (2012)
- J.W. McGinity and F. Zhang “Melt-Extruded Controlled Release Oral Dosage Forms”, , Chapter 10, Pharmaceutical Extrusion Technology, Volume 133 from Drugs and the Pharmaceutical Sciences series, 1st Edition, Ed. I. Ghebre-Sellassie and C. Martin pp. 183-208, 26 total pages, Marcel Dekker (2003)
- J.W. McGinity, J.J. Koleng, M.A. Repka, and F. Zhang “Hot-Melt Extrusion Technology”, Volume 19 of the Encyclopedia of Pharmaceutical Technology, 2nd Edition, Ed. J. Swarbrick and J.C. Boylan, pp. 203-226, 24 total pages, Marcel Dekker, (2000)