The Molecular Pharmaceutics & Drug Delivery Seminar Series Presents:
Dr. Hamideh Parhiz, Pharm.D., Ph.D., Assistant Professor of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania
Cell-Specific Targeted LNP-RNA for In Vivo Cellular Reprogramming
Tuesday, April 15, 2025
11:00 a.m. – 12:00 p.m.
PHR 4.114
In-Person/Hybrid
Dr. Parhiz leads the targeted LNP delivery program. She is also the co-director of targeting core at Penn Institute for RNA Innovation. Her expertise is developing novel nucleic acid delivery systems including a new generation of targeted LNP-mRNA therapeutics for a variety of non-vaccine applications such as blood gene disorders, cancer, fibrosis, and acute inflammatory conditions. The Parhiz lab investigates the mechanisms underlying the enhancement of delivery systems such as the ones related to more favorable pharmacokinetic profile, to apply those principles in designing more effective gene and mRNA therapeutics. Hamideh’s work has resulted in several publications in high-ranked journals including two papers in Science magazine and several patents. Her work in designing an efficient targeted LNP-mRNA platform is now the basis for academic programs as well as industrial product developments in companies such as Capstan Therapeutics.