This group of Pharmacy faculty has focused research efforts in the area of infectious disease to understand pathogenic mechanisms, to discover and develop protein and small molecule therapeutics, and to develop other anti-infective technologies including novel vaccination methods.
Faculty Participants: College of Pharmacy
Work in Dr. Croyle’s lab focuses on the development of novel methods for rapid immunization against dangerous pathogens like Ebola. Additional projects focus on the long-term physiological effects of virus infection with respect to the immune response and drug metabolism.
Research focuses on rational drug and vaccine delivery including nanoparticles for vaccine and anti-cancer drug delivery, non-invasive immunization onto the skin, and cancer chemo-immunotherapy.
Dr. Duhon practices in the Adult Internal Medicine setting, where he is involved with the medical management of the adult hospitalized patient. His principal interests include infectious diseases, diabetes, and innovative pedagogical techniques.
Dr. Frei’s translational research activities involve the application and critical evaluation of novel technologies (including anti-infectives) in both institutional and community healthcare settings. His approach can best be described as a mixture of pharmacoepidemiology, health services research, health disparities research, and microbial genomics.
DNA repair and genomic instability; infection-mediated inflammation and cancer; DNA damage response in preeclampsia.
Research focus is the clinical and molecular epidemiology of Staphylococcus aureus infections. Her research uses an integrated translational approach to develop innovative S. aureus prevention and treatment strategies
Liu’s research lies at the crossroads of chemistry and biology. His group is currently working on three general areas with the focus aimed at the elucidation of the mechanisms of novel enzymatic reactions and the design of methods to control and/or regulate their functions.
Dr. Reveles’ research focus is the prevention and treatment of Clostridium difficile infections and innovative methods to improve the translation of clinical research findings into practice.
Work in Dr. Smyth’s lab focuses on the development of novel methods for drug delivery including inhalation, nasal, transdermal, ophthalmic, and oral delivery systems for a variety of diseases. Translation of these technologies to the clinic is the long-term goal of the lab and is supported by developing a mechanistic understanding of the complex physical and biological systems.