Pharmacology & Toxicology

In a recent article in the Proceedings of the National Academy of Sciences (PNAS), ongoing research into the causes of manganese-induced parkinsonism has revealed a possible treatment option. Dr. Somshuvra Mukhopadhyay and a team of researchers have released new findings that the PHD2 inhibitor, which is the cell’s master oxygen sensor, has a second physiologically essential function – to also act as the cell’s manganese sensor.

The Division of Pharmacology & Toxicology's Karen Vasquez, Ph.D. talked to Chemistry World's Rachel Brazil on genetic instability in disease and evolution of course related to Z-DNA. Dr. Vasquez's research focuses on genome instability, DNA damage and mechanisms of repair.

The Hill covers a new report headed by Professor of Pharmacology & Toxicology Andrea Gore, Ph.D. that draws attention to the link between plastics, pesticides and forever chemicals and the growing incidence of endocrine-associated disorders over the last two decades.